Drugs Interaction of Anticancer Agents

Crude drugs as anticancer agents.

Although tremendous progress has been made in basic cancer biology and in the development of novel cancer treatments, cancer remains a leading cause of death in the world. The etiopathogenesis of cancer is complex. Besides genetic predisposition, known environmental factors associated with cancer are: diet, lifestyle, and environmental toxins. Toxicity of drugs and eventual relapse of cancers c...

Antibacterial and Anticancer Drugs - Interaction with DNA

ONIOM studies of interaction between single-walled carbon nanotube and gallates derivatives as anticancer agents

Objective(s): The novel 7-hydroxycoumarinyl gallates derivatives are detected in many pharmaceutical compounds like anticancer and antimicrobial agents. Whereas carbon nanotubes (CNTs) have been discussed for nanomedicine applications and in particular as drug delivery systems. The capability of armchair (5, 5) SWCNT -based drug delivery system in the therapy of anticancer has been investigated...

Quantitative measure of cytotoxicity of anticancer drugs and other agents.

Many anticancer drugs act on cancer cells to promote apoptosis, which includes impairment of cellular respiration (mitochondrial O(2) consumption). Other agents also inhibit cellular respiration, sometimes irreversibly. To investigate the sensitivity of cancer cells to cytotoxins, including anticancer drugs, we compare the profiles of cellular O(2) consumption in the absence and presence of the...

Chromatography of Anticancer Drugs

Chromatographic techniques have been developed and successfully applied for the analysis of a considerable of number of organic and inorganic compounds present at trace level in sometimes complicated accompanying matrices. The rapid development of new chromatographic instrumentation and separation strategies resulted in the increase of the number of chromatographic technologies with higher sepa...